| SEARCH | The position of a substring within a larger text string. |
| SEC | (2013) The secant of an angle. |
| SECH | (2013) The hyperbolic secant of an angle. |
| SECOND | The number of seconds given a date serial number. |
| SERIESSUM* | The sum of a power series based on a formula. |
| SHEET | (2013) The sheet number of the referenced sheet. |
| SHEETS | (2013) The number of sheets in a reference. |
| SIGN | The numerical value indicating if a number is positive or negative. |
| SIN | The sin of an angle in radians. |
| SINH | The hyperbolic sine of a number. |
| SKEW | The number representing the skewness of a distribution. |
| SKEW.P | (2013) The skewness of a distribution based on a population. |
| SLN | The depreciation of an asset in a single period (straight-line method). |
| SLOPE | The slope of a linear regression line through the given data points. |
| SMALL | The Kth smallest value in a list or array of numbers. |
| SQL.REQUEST | Connects to an external data source and executes a query. |
| SQRT | The positive square root of a number. |
| SQRTPI* | The square root of a number multiplied by PI. |
| STANDARDIZE | The normalized value from a distributed characterised by a mean and a standard deviation. |
| STDEV | The standard deviation based on a sample. |
| STDEV.P | (2010 - STDEVP) The standard deviation based on an entire population. |
| STDEV.S | (2010 - STDEV) The standard deviation based on a sample. |
| STDEVA | The standard deviation based on a sample (including text and logical values). |
| STDEVP | The standard deviation based on an entire population. |
| STDEVPA | The standard deviation based on an entire population (including text and logical values). |
| STEYX | The standard error of a regression. |
| SUBSTITUTE | The text string with a substring substituted for another substring. |
| SUBTOTAL | The subtotal of values in a list or database column. |
| SUM | The total value of the numbers in a list or cell range. |
| SUMIF | The total value of the numbers that satisfies a condition. |
| SUMIFS | (2007) The total value of the numbers that satisfy multiple conditions. |
| SUMPRODUCT | The sum of the product of one or more arrays of values. |
| SUMSQ | The sum of the squares of all the values in a list or cell range. |
| SUMX2MY2 | The sum of the difference of squares of corresponding values in two arrays. |
| SUMX2PY2 | The sum of the sum of squares of corresponding values in two arrays. |
| SUMXMY2 | The sum of squares of differences of corresponding values in two arrays. |
| SYD | The depreciation of an asset in a single period (sum-of-years digits method). |