Detect Keystrokes

It is possible to catch any keystrokes that are made while a Form is displayed by implementing the IMessageFilter interface.
The following code will catch the Excape key on a key down.

Public Class frmMain 
   Inherits System.Windows.Forms.Form 

   Implements IMessageFilter 

   Private Function PreFilterMessage(ByRef m As Message) As Boolean Implements IMessageFilter.PreFilterMessage 
      
   End Function 

   Private Sub frmMain_Load(ByVal sender As System.Object, _ 
                            ByVal e As System.EventArgs) _ 
                            Handles MyBase.Load 

      Application.AddMessageFilter(Me) 
   End Sub 

End Class 

System.Windows.Forms.Keys

System.Windows.Forms.Keys.ShiftKey 
System.Windows.Forms.Keys.ControlKey